Molecular cloning of the feline CD8β‐chain
نویسندگان
چکیده
منابع مشابه
Molecular cloning and sequencing of feline CD7.
Human CD7 is one of the earliest molecules to appear in T cell development. In this study, putative feline CD7 cDNA was identified based on its similarities with human and mouse CD7 genes. The feline CD7 cDNA contained an open reading frame consisting of 630 nucleotides. The amino acid sequence of feline CD7 had 47.7% identity with that of human CD7, and 52.9% with that of mouse CD7. In additio...
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Feline immunodeficiency virus (FIV) is a T-lymphotropic retrovirus associated with immunodeficiency and opportunistic infections in cats. The discovery of FIV provides an opportunity for the development of a small animal model for AIDS. To initiate the molecular and biological characterization of FIV, cDNA clones were synthesized and used to isolate a proviral clone of FIV. Molecular cross-hybr...
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We cloned a cDNA fragment encoding a feline homologue of L-selectin (CD62L). The extracellular region of the feline CD62L fragment contained a calcium-dependent (C-type) lectin domain, an epidermal growth factor-like domain, and two Sushi/CCP/SCR domains. The flow cytometric analysis confirmed that the feline CD62L molecule, which was expressed 293T cells, retained an epitope recognized by an a...
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BACKGROUND Glucokinase (GK) is a metabolic enzyme encoded by the GCK gene and expressed in glucose-sensitive tissues, principally pancreatic islets cell and hepatocytes. The GK protein acts in pancreatic islets as a "glucose sensor" that couples fluctuations in the blood glucose concentration to changes in cellular function and insulin secretion. GCK and GK have proposed importance in the devel...
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Feline Caliciviral infection is typically associated with mild depression, sneezing, ocular and nasal discharges, and often mouth ulceration. However, isolates vary in their pathogenicity. Some isolates reproducibly cause a more severe syndrome; some induce oral or nasal ulceration alone; some induce an interstitial pneumonia and some appear to be apathogenic[ 1-31. Infection with feline calici...
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ژورنال
عنوان ژورنال: Immunology
سال: 1996
ISSN: 0019-2805,1365-2567
DOI: 10.1046/j.1365-2567.1996.d01-710.x